COVID is surging in the world’s most vaccinated country. Why?


Houses in the city of Victoria, the capital of Seychelles.
Shutterstock

C Raina MacIntyre, UNSWThe small archipelago nation of Seychelles, northeast of Madagascar in the Indian Ocean, has emerged as the world’s most vaccinated country for COVID-19.

Around 71% of people have had at least one dose of a COVID vaccine, and 62% have been fully vaccinated. Of these, 57% have received the Sinopharm vaccine, and 43% AstraZeneca.

Despite this, there has been a recent surge in cases, with 37% of new active cases and 20% of hospital cases being fully vaccinated. The country has had to reimpose some restrictions.

How can this be happening? There are several possible explanations:

  1. the herd immunity threshold has not been reached — 62% vaccination is likely not adequate with the vaccines being used
  2. herd immunity is unreachable due to inadequate efficacy of the two vaccines being used
  3. variants that escape vaccine protection are dominant in Seychelles
  4. the B1617 Indian variant is spreading, which appears to be more infectious than other variants
  5. mass failures of the cold-chain logistics needed for transport and storage, which rendered the vaccines ineffective.

What does the country’s experience teach us about variants, vaccine efficacy and herd immunity?

Let’s break this down.

Variants can escape vaccine protection

There are reports of the South African B.1.351 variant circulating in Seychelles. This variant shows the greatest ability to escape vaccine protection of all COVID variants so far.

In South Africa, one study showed AstraZeneca has 0-10% efficacy against this variant, prompting the South African government to stop using that vaccine in February.

The efficacy of the Sinopharm vaccine against this variant is unknown, but lab studies show some reduction in protection, based on blood tests, but probably some protection.

However, no comprehensive surveillance exists in the country to know what proportion of cases are due to the South African variant.

The UK variant B117, which is more contagious than the original strain, became the dominant variant in the United States. But the US still achieved a dramatic reduction in COVID-19 cases through vaccination, with most people receiving the Pfizer and Moderna vaccines.

Israel, where the UK variant was dominant, also has a very high vaccination rate, having vaccinated nearly 60% of its population with Pfizer. It found 92% effectiveness against any infection including asymptomatic infection, and Israel has seen a large drop in new cases.

The United Kingdom has used a combination of Pfizer and AstraZeneca vaccines. More than 50% of the population have had a single dose and almost 30% are fully vaccinated. The country has also seen a significant decline in case numbers.

But there’s a current surge of cases in northwest England, with most new cases in the city of Bolton being the Indian variant. This variant is also causing outbreaks in Singapore, which had previously controlled the virus well.

Seychelles needs to conduct urgent genome sequencing and surveillance to see what contribution variants of concern are making, and whether the Indian variant is present.

If the South African variant is dominant, the country needs to use a vaccine that works well against it. Many companies are making boosters targeted to this variant, but for now, Pfizer would be an option. In Qatar, local researchers found Pfizer had 75% effectiveness against the South African variant.




Read more:
New COVID variants have changed the game, and vaccines will not be enough. We need global ‘maximum suppression’


We need to use high-efficacy vaccines to achieve herd immunity

The reported efficacy of Sinopharm is 79% and AstraZeneca is 62-70% from phase 3 clinical trials.

Our research at the Kirby Institute showed that, in New South Wales, Australia, using a vaccine with 90% efficacy against all infection means herd immunity could be achieved if 66% of the population was vaccinated.

However, using lower efficacy vaccines means more people need to be vaccinated. If the vaccine is 60% effective, the proportion needing to be vaccinated rises to 100%.

When you get an efficacy of less than 60%, herd immunity is not achievable.

However, these calculations were done for the regular COVID-19 caused by the D614G variant which dominated in 2020. This has a reproductive number (R0) of 2.5, meaning people infected with the virus on average infect 2.5 others.

But the B117 variant is 43-90% more contagious than D614G, so the R0 may be up to 4.75. This will require higher vaccination rates to control spread.

What’s more, the Indian variant B1617 has been estimated to be at least 50% more contagious than B117, which could take the R0 to over 7, and takes us into uncharted territory.

This could explain the catastrophic situation in India, but also raises the stakes for vaccination, as lower efficacy vaccines will not be able to contain such highly transmissible variants effectively.

Herd immunity is still possible, but depends on the efficacy of the vaccine used and the proportion of people vaccinated.

A UK modelling study found using very low efficacy vaccines would result in the economy barely breaking even over ten years because it would fail to control transmission. On the other hand, using very high efficacy vaccines would result in much better economic outcomes.

Vaccinating the world is the only way to end the pandemic

As the pandemic continues to worsen in some parts of the world, the risk increases of more dangerous mutations that are vaccine-resistant or too contagious to control with current vaccines.

Keeping up with mutations is like whack-a-mole while the pandemic is raging.

The take-home message for our pandemic exit strategy is that the sooner we get the whole world vaccinated, the sooner we will control emergence of new variants.




Read more:
3 ways to vaccinate the world and make sure everyone benefits, rich and poor


The Conversation


C Raina MacIntyre, Professor of Global Biosecurity, NHMRC Principal Research Fellow, Head, Biosecurity Program, Kirby Institute, UNSW

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Plinky Prompt: The Most Important Thing I Learned This Year


Interesting, 01

This will be a lesson I should have learnt some time ago, but seemingly forgot. It’s a really simple lesson really, though apparently easily forgotten. Simply put – don’t over commit at work. Certainly, work to the appropriate level, not denying that – just don’t over do it. What I mean is, putting in a heap of extra hours doesn’t do your health any good – physically, mentally, etc. So keep the job in perspective and in balance with the rest of life.

Powered by Plinky

Plinky Prompt: Share the Most Dangerous Thing You've Ever Done For Fun



Waterfall

Hmmm, I generally play it safe I have to admit – but occasionally I do do something stupid and/or dangerous during my normal activities. This generally happens when I’m out bushwalking, though I find myself being more cautious these days.

Some of the most dangerous situations I have found myself in while bushwalking have been when trying to ascend/descend waterfalls. I have fallen on several occasions now and on one occasion suffered some injuries that required me to abandon the rest of my walk/climb on that day.

On another occasion I fell and landed far too close to what was effectively a spear, right beside by throat.

Some falls like these do tend to lead you to more caution in future times.

Powered by Plinky

 

Australia: Sharia Law Push Not Backed by Most Australian Muslims


The push for Sharia Law adoption in Australia is not widely supported by Australian Muslims according to a report in The Australian newspaper.

For more visit:
http://www.theaustralian.com.au/business/legal-affairs/sharia-push-surprises-muslim-bodies/story-e6frg97x-1226068259507

 

Religious Conversion Worst Form of ‘Intolerance,’ Bhutan PM Says


Propagation of religion is allowable – but not seeking conversions, top politician says.

THIMPHU, Bhutan, April 13 (CDN) — In the Kingdom of Bhutan, where Christianity is still awaiting legal recognition, Christians have the right to proclaim their faith but must not use coercion or claim religious superiority to seek conversions, the country’s prime minister told Compass in an exclusive interview.

“I view conversions very negatively, because conversion is the worst form of intolerance,” Jigmi Yoser Thinley said in his office in the capital of the predominantly Buddhist nation.

Christian leaders in Bhutan have told Compass that they enjoy certain freedoms to practice their faith in private homes, but, because of a prohibition against church buildings and other restrictions, they were not sure if proclamation of their faith – included in international human rights codes – was allowed in Bhutan.

Prime Minister Thinley, who as head of the ruling party is the most influential political chief in the country, said propagation of one’s faith is allowed, but he made it clear that he views attempts to convert others with extreme suspicion.

“The first premise [of seeking conversion] is that you believe that your religion is the right religion, and the religion of the convertee is wrong – what he believes in is wrong, what he practices is wrong, that your religion is superior and that you have this responsibility to promote your way of life, your way of thinking, your way of worship,” Thinley said. “It’s the worst form of intolerance. And it divides families and societies.”

Bhutan’s constitution does not restrict the right to convert or proselytize, but some Non-Governmental Organizations have said the government effectively limits this right by restricting construction of non-Buddhist worship buildings and celebration of some non-Buddhist festivals, according to the U.S. Department of State’s 2010 International Religious Freedom Report.

It adds that Bhutan’s National Security Act (NSA) further limits proclamation of one’s faith by prohibiting “words either spoken or written, or by other means whatsoever, that promote or attempt to promote, on grounds of religion, race, language, caste, or community, or on any other ground whatsoever, feelings of enmity or hatred between different religious, racial, or language groups or castes and communities.” Violation of the NSA is punishable by up to three years’ imprisonment, though whether
any cases have been prosecuted is unknown, according to the State Department report.

Bhutan’s first democratic prime minister after about a century of absolute monarchy, Thinley completed three years in office last Thursday (April 7). While he affirmed that it is allowable for Christians to proclaim their faith – a practice commanded by Christ, with followers agreeing that it is the Holy Spirit, not man, that “converts” people – Thinley made his suspicions about Christians’ motives manifest.

“Any kind of proselytization that involves economic and material incentives [is wrong],” he said. “Many people are being converted on hospital beds in their weakest and most vulnerable moments. And these people are whispering in their ears that ‘there is no hope for you. The only way that you can survive is if you accept this particular religion.’ That is wrong.”

Thinley’s suspicions include the belief that Christians offer material incentives to convert.

“Going to the poor and saying, ‘Look, your religion doesn’t provide for this life, our religion provides for this life as well as the future,’ is wrong. And that is the basis for proselytization.”

Christian pastors in Thimphu told Compass that the perception that Bhutan’s Christians use money to convert the poor was flawed.

The pastors, requesting anonymity, said they prayed for healing of the sick because they felt they were not allowed to preach tenets of Christianity directly. Many of those who experience healing – almost all who are prayed for, they claimed – do read the Bible and then believe in Jesus’ teachings.

Asked if a person can convert if she or he believed in Christianity, the prime minister replied, “[There is] freedom of choice, yes.”

In his interview with Compass, Thinley felt compelled to defend Buddhism against assertions that citizens worship idols.

“To say that, ‘Your religion is wrong, worshiping idols is wrong,’ who worships idols?” he said. “We don’t worship idols. Those are just representations and manifestations that help you to focus.”

Leader of the royalist Druk Phuensum Tshogpa party, Thinley is regarded as a sincere politician who is trusted by Bhutan’s small Christian minority. He became the prime minister in April 2008 following the first democratic election after Bhutan’s fourth king, Jigme Singye Wangchuck, abdicated power in 2006 to pave the way toward democracy.

Until Bhutan became a constitutional monarchy in 2008, the practice of Christianity was believed to be banned in the country. The constitution now grants the right to freedom of thought, conscience and religion to all citizens. It also states that the king is the protector of all religions.

Thus far, the Religious Organisations Act of 2007 has recognized only Buddhist and Hindu organizations. As a result, no church building or Christian bookstore has been allowed in the country, nor can Christians engage in social work. Christianity in Bhutan remains confined to the homes of local believers, where they meet for collective worship on Sundays.

Asked if a Christian federation should be registered by the government to allow Christians to function with legal recognition, Thinley said, “Yes, definitely.”

The country’s agency regulating religious organizations under the 2007 act, locally known as the Chhoedey Lhentshog, is expected to make a decision on whether it could register a Christian federation representing all Christians. The authority is looking into provisions in the law to see if there is a scope for a non-Buddhist and non-Hindu organization to be registered. (See http://www.compassdirect.com, “Official Recognition Eludes Christian Groups in Bhutan,” Feb. 1.)

On whether the Religious Organisations Act could be amended if it is determined that it does not allow legal recognition of a Christian federation, the prime minister said, “If the majority view and support prevails in the country, the law will change.”

Thinley added that he was partially raised as a Christian.

“I am part Christian, too,” he said. “I read the Bible, occasionally of course. I come from a traditional [Christian] school and attended church every day except for Saturdays for nine years.”

A tiny nation in the Himalayas between India and China, Bhutan has a population of 708,484 people, of which roughly 75 percent are Buddhist, according to Operation World. Christians are estimated to be between 6,000 to nearly 15,000 (the latter figure would put Christians at more than 2 percent of the population), mostly from the south. Hindus, mainly ethnic Nepalese, constitute around 22 percent of the population and have a majority in the south.

 

Religious ‘Competition’

Bhutan’s opposition leader, Lyonpo Tshering Togbay, was equally disapproving of religious conversion.

“I am for propagation of spiritual values or anything that allows people to be good human beings,” he told Compass. “[But] we cannot have competition among religions in Bhutan.”

He said, however, that Christians must be given rights equal to those of Hindus and Buddhists.

“Our constitution guarantees the right to freedom of practice – full stop, no conditions,” he said. “But now, as a small nation state, there are some realities. Christianity is a lot more evangelistic than Hinduism or Buddhism.”

Togbay said there are Christians who are tolerant and compassionate of other peoples, cultures and religions, but “there are Christians also who go through life on war footing to save every soul. That’s their calling, and it’s good for them, except that in Bhutan we do not have the numbers to accommodate such zeal.”

Being a small nation between India and China, Bhutan’s perceived geopolitical vulnerability leads authorities to seek to pre-empt any religious, social or political unrest. With no economic or military might, Bhutan seeks to assert and celebrate its sovereignty through its distinctive culture, which is based on Buddhism, authorities say.

Togbay voiced his concern on perceived threats to Bhutan’s Buddhist culture.

“I studied in a Christian school, and I have lived in the West, and I have been approached by the Jehovah’s Witness – in a subway, in an elevator, in a restaurant in the U.S. and Switzerland. I am not saying they are bad. But I would be a fool if I was not concerned about that in Bhutan,” he said. “There are other things I am personally concerned about. Religions in Bhutan must live in harmony. Too often I have come across people who seek a convert, pointing to statues of our deities and saying
that idol worship is evil worship. That is not good for the security of our country, the harmony of our country and the pursuit of happiness.”

The premise of the Chhoedey Lhentshog, the agency regulating religious organizations, he said, “is that all the different schools of Buddhism and all the different religions see eye to eye with mutual respect and mutual understanding. If that objective is not met, it does not make sense to be part of that.”

It remains unclear what the legal rights of Christians are, as there is no interaction between the Christians and the government. Christian sources in Bhutan said they were open to dialogue with the government in order to remove “misunderstandings” and “distrust.”

“Thankfully, our political leadership is sincere and trustworthy,” said one Christian leader.

Asserting that Christians enjoy the right to worship in Bhutan, Prime Minister Thinley said authorities have not interfered with any worship services.

“There are more Christian activities taking place on a daily basis than Hindu and Buddhist activities,” he added.

Report from Compass Direct News
http://www.compassdirect.org

Plinky Prompt: The Most Trouble I've Gotten Myself Into…


Caution: Overly Tall Morons Might Hit Heads

Not sure whether this would be the most trouble I have gotten into, but it did have the potential to be so.

What happened? When I was in primary school (aged about 10 I suppose) I hit a kid with an iron bar across the head. I hid under the school building all day before going home at home time. The teachers had been searching for me all day. The following day at school nothing happened – seems they all forgot about it.

Powered by Plinky

Plinky Prompt: What Do You Miss Most About Childhood?


Street Cricket; Agra, Uttar Pradesh, India

I have never really thought about what I miss most about my childhood – but I do remember the cricket matches I had with my brother. We used to play test matches – he would have the Aussie cricket team and I’d have the Windies. Good fun that.

Powered by Plinky

Plinky Prompt: Would You Rather Be Super Intelligent or Extremely Good Looking?


Intellectual Incitement Ahead

Hmmm – this is a rather self-centered question. The answer I have for this question is that I’m really quite content with who I am. I am what God had made me to be and with that I am content.

In human terms I know I am not the most attractive/good looking guy that is getting about. I’d have to say I’m fairly average – if not below average – by this current age’s philosophy of good looks. One of the reasons why I’m still single I guess.

I also wouldn’t describe myself as super intelligent, but am thankful for having a degree of intelligence that allows me to be a little intellectual. Perhaps, another reason I am still single – lol.

So to answer this question – I am content with what God has made me to be and what he has fashioned me to be via His providential dealings.

Powered by Plinky

Buddhists in India Assault Christian Aid Worker, Friend


Assailants, still at large, abduct and threaten blind volunteer, associate and pregnant wife.

NEW DELHI, September 6 (CDN) — A visually impaired Christian and his friend accused drunken Buddhists of abducting and assaulting them last week after the blind volunteer distributed relief material in a Buddhist-majority town in a region of India devastated by recent floods.

The attackers are still at large after the assault on Wednesday (Sept .1) in the town of Leh in Jammu and Kashmir state’s Ladakh region, where flooding and landslides destroyed hundreds of houses and killed around 200 people on Aug. 6.

The attackers, identified as members of the Ladakh Buddhist Association (LBA), one of the region’s largest and most influential Non-Governmental Organizations, abducted Ram Kumar Thapa, Stanzin Chosphel and his pregnant wife Putali Sherpa because of their Christian faith and beat the men, the victims said.

Thapa, a blind music teacher in his 30s, was abducted from Mahabodhi Gate in Choglamsar area in Leh, where he was distributing relief material, at around 7 p.m. on Wednesday, according to the complaint he filed on Thursday (Sept. 2) with the Jammu and Kashmir State Human Rights Commission.

LBA members were upset that Thapa was preaching Christianity to displaced residents, according to his complaint. The Evangelical Fellowship of India Commission on Relief, a Christian relief agency, is rebuilding homes for the displaced people, mostly Buddhists, in the area.

“I was attacked physically by several unknown assailants before other witnesses nearby,” Thapa stated in the complaint. “Then these men forced me into a vehicle and continued beating me all over my body as they spoke in Ladakhi to each other.”

Thapa, from the eastern state of West Bengal, also stated that the Buddhists contemplated killing him. “They discussed whether to take my life or return to the ‘office,’” he said.

The assailants took Thapa to the office of the LBA in Soma Monastery, where a Buddhist monk was also present, and beat him again, he stated. He was then moved to a room where he could hear the voice of his friend, Chosphel, with his pregnant wife.

Chosphel, a convert from Buddhism, is from Ladakh and his wife is from Nepal. The Buddhist assailants had taken them from their house in the Skalzaling area in Leh after Thapa, under pressure from the LBA members, identified them as his associates, according to the Christian victims.

The attackers showed Thapa’s bruised and bleeding face to Chosphel to warn him against continuing as a Christian, Thapa stated. He was then taken back to the vehicle.

“They placed a gunny sack with a rope onto my lap and explained that this would be my last bed … [after] they throw me into the Indus River and see if a blind man can swim and save himself,” Thapa stated. “I became terribly afraid, since I could smell alcohol on their breath as we sat in the vehicle.”

Thapa begged that his life be spared “so I could see my wife, who must be worried since it was late now.” The kidnappers replied, “Your wife will see you when she finds your body by the river bank,” he stated.

Thapa and his wife, also visually impaired, teach and live at Mahabodhi Residential School for handicapped children.

Thapa stated that when he asked what they wanted from him, “they said I had to leave Ladakh with my family within two days or else they would kill me and my family. It was around 1 a.m. when they dropped me back to my house, bruised and trembling.”

Thapa went to the Housing Colony Police Station on Thursday (Sept. 2) and found out that Chosphel also was there to file his complaint.

Chosphel confirmed that the “office” they were taken to belonged to the LBA. In his complaint to the commission, Chosphel said that around 15 “heavily drunken” men came to abduct him and his wife in their black Bolero, a mid-size SUV.

In the courtyard of the LBA facility, the Buddhists beat Chosphel before his wife, who pleaded for them to stop and asked why they were being assaulted.

“They threatened to beat her as well if she did not keep silent,” Chosphel stated. “Then they dragged me into a room and gagged my mouth so I could not cry out as they beat me with rubber pipes and rods and fists continuously. All along they kept telling me to leave my wife and also renounce my faith in Christianity and return to Buddhism.”

The men released the couple at around 12:30 a.m. after giving them two days to leave Leh or convert to Buddhism, Chosphel stated, “or else they will chop my wife into pieces and kill me and also kill my family … who are still practicing Buddhists.”

The attackers also confiscated their mobile phones.

The victims told Compass that they were still facing a threat on their lives even after filing complaints with police.

Additional Superintendent of Police Stanzin Nurboo told Compass that no one had been arrested because the victims could not name the accused.

Chosphel and his wife, however, told Compass that they would be able to identify the attackers if they saw their faces; at press time, however, they said police had not contacted any of them to do so.

Religious conversion is a sensitive issue in Leh, which borders Pakistan and Tibet, as it is seen as an attack on its distinct religious and cultural identity.

Citing religious and cultural differences with the otherwise Muslim-majority Jammu and Kashmir state, some residents of Ladakh have been asking for union territory status for the region.

As a concession, the Ladakh region was bifurcated into Muslim-majority Kargil district and Buddhist-majority Leh district in 1979, and the Ladakh Autonomous Hill Development Council was also created in 1995 to grant some autonomy to Leh and Kargil districts.

The government of Jammu and Kashmir continues to have responsibility for maintaining law and order and is in charge of the judicial system, communications and higher education.

Of the population of 117,232, over 80 percent of the people in Leh are Buddhist. Muslims make up around 15 percent of the population, Hindus 3 percent and Christians 0.2 percent.

Report from Compass Direct News

Plinky Prompt: What Part of Life Confuses You the Most?


For me this is more of a question of disillusionment than confusion.

Question Mark Sign On Hobson’s Old Building, Corner Of Henry & Main (Honor, MI)

OK, this is a difficult question to answer. I don’t know that there is anything that really confuses me too much. That isn’t to say I’m smart, only to say that the Bible generally gives me the answers to all of the questions that generally confuse people.

I think that which gives me the most difficulty is an area that I know the answer to – at least in theory, yet in practical terms it seems very difficult to fathom. It is a religious question (Christian). Why is it that people who know the truth behave/live in a manner opposed to that truth they profess? The answer of course is sin (put simply), but this widespread issue is one that does from time to time bring me some disillusionment.