Taking one for the team: 6 ways our cells can die and help fight infectious disease

White blood cells dying.

Georgia Atkin-Smith, La Trobe University and Ivan Poon, La Trobe UniversityWe have all heard of COVID-19, the flu and bacterial infections. But what is actually happening to our cells when we contract these diseases? Many of our body’s cells don’t live to tell the tale. But cell death isn’t necessarily a bad thing — in fact, the death of infected cells can provide a sacrificial mechanism to stop pathogens in their tracks before they can spread through our body.

Over the years, researchers have realised there are many ways for our cells to die. Our genetics contain a comprehensive “licence to die”, with the route to cell death dictated by both the type of the cell and the pathogen. Let’s check some out:

The dancing death

In the time it takes you to read this sentence, ten million cells in your body will have died, through a type of death called apoptosis. This term, coined in 1972 by Australian pathologist John Kerr, comes from the Greek phrase for “leaves falling from a tree”.

Apoptosis is the most common form of cell death, and has also been nicknamed the “dance of death”, because of the extraordinary shape changes exhibited by the cells under a microscope as they sacrifice themselves.

For example, apoptotic cells dying from radiation or infection with influenza A virus (aka, the flu) generate large, bubble-like structures on their surface called blebs, before shooting out long beaded necklace-like protrusions and finally shattering into pieces.

The death of flu-infected cells is suggested to both aid and limit viral spread. Nevertheless, it’s a spectacular event to witness (and an excellent reminder to get your flu shot this winter).

White blood cell blebbing and dying.

Out with a bang

Vaccinia virus is used worldwide to vaccinate against smallpox. In fact, it was the very first vaccine, developed in 1796 by Edward Jenner.

We now also know that vaccinia virus can make our cells more sensitive to a particular type of cell death, caused by a molecule called TNF. This can help prevent the disease spreading by killing off infected cells before the virus has a chance to replicate.

Many of our cells have a roughly spherical or balloon-like shape, encapsulated by a protective layer called the cell membrane. Just like bursting a balloon with a pin, puncture to the cell membrane marks the point of no return.

This process occurs during necroptosis — an explosive type of cell death in which proteins inside the cell punch holes in the membrane. The cell pops and dies, shutting down the machinery needed for viral replication.

The spider web of death

When they aren’t busy haunting our nightmares, spiders can be found weaving silken masterpieces of extraordinary detail and strength. The web of a golden orb weaving spider, for example, is strong enough to entangle small birds.

On a smaller but equally impressive scale, our immune system contains specialised cells called neutrophils that can weave a deadly web of their own and entrap bacteria. Neutrophils gallantly sacrifice themselves in the process of casting their web, in a type of cell death perhaps fittingly called NETosis.

When infected with bacteria such as Streptococcus pneumoniae, which causes pneumonia and meningitis, neutrophils eject a specialised web made from their own DNA. These webs can entangle nearby bacteria to prevent their escape until other immune cell reinforcements arrive to clear the infection. Sometimes, proteins found in these webs can also kill the bacteria – quite an impressive defence mechanism!

There are a surprising number of ways cells can lay down their lives for the greater good.
Author provided

The last meal

Just as our bodies are compartmentalised into organs such as the stomach, liver or heart, our individual cells also have specialised compartments. One of the cell’s “stomachs” (a structure called the “autophagosome”) engulfs and digests cellular contents such as damaged molecules through the process of autophagy.

However, in some circumstances, the machinery that drives this Pac-Man-style action can also facilitate the cell’s demise. Coincidentally, the bacteria Helicobacter pylori can infect cells of the human stomach lining, called epithelial cells, which can cause ulcers and gastritis. The cells can respond with a process called autophagic cell death, in which the induction of autophagy causes the cell to die.

A fiery death

Pyromania, derived from the Greek word pyr, meaning fire, is an obsessive desire to set things ablaze. Some of our immune cells also have the ability to self-immolate and cause inflammation as part of our response to infection.

Since its relatively recent discovery in 2001, this type of cell death, called pyroptosis, has become a hot topic (sorry) among cell biologists, and is often facilitated by a molecular complex called the inflammasome.

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Read more:
What is autoinflammatory disease, the rare immune condition with waves of fever?

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In 2021, understanding pyroptosis is more important than ever, as it has been linked to infection with SARS-CoV-2 infection, the virus that causes COVID-19.

Activation of the factors that cause pyroptosis may help explain the excessive inflammation seen in patients with severe COVID-19. And this could potentially offer a new way to combat the disease.

Overdosing on iron and fat

There’s no doubt the key to a long and healthy life is a balanced diet and exercise. However, sometimes we can’t resist the urge to devour a burger and fries with ice cream for dessert. With enough hard work, we can burn it off again. But for individual cells, overindulging can be fatal.

Too much iron and/or harmful types of fat molecules can cause cells to die by ferroptosis. Cells infected with Mycobacterium tuberculosis, the bacterium that causes TB, can increase their iron content and cause ferrototic cell death! Pass the salad, thanks.

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Read more:
Tick, tock… how stress speeds up your chromosomes’ ageing clock

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The survival of the human body is a fine balancing act between cell growth and cell death. Understanding our cells’ complex “licence to die” could give us new ways to combat disease.

Georgia Atkin-Smith, Research scientist, La Trobe University and Ivan Poon, Associate Professor, Biochemistry, La Trobe University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Iran: Persecution News Update

The link below is to an article reporting on persecution news from Iran, where prison guards have raided cells of Christians and stolen personal items.

For more visit:
Guards Raid Cells of Christians in Evin Prison

Iranian Authorities Release Assyrian Pastor on Bail

Accused of ‘converting Muslims,’ church leader faces trial – and threat of murder.

ISTANBUL, April 5 (CDN) — An Assyrian pastor the Iranian government accused of “converting Muslims” has been released from prison on bail and is awaiting trial.

The Rev. Wilson Issavi, 65, was released from Dastgard prison in Isfahan last week. Conflicting reports indicated Issavi was released sometime between Sunday (March 28) and Tuesday morning (March 30).

On Feb. 2, State Security Investigations (SSI) agents arrested Issavi shortly after he finished a house meeting at a friend’s home in Isfahan. Along with the accusation of “converting Muslims,” the pastor is charged with not co-operating with police, presumably for continuing to hold such house meetings after police sealed the Evangelical Church of Kermanshah and ordered him not to reopen it.

After his arrest, Issavi was held at an unmarked prison facility in Isfahan and apparently tortured, according to a Christian woman who fled Iran and knows Issavi and his family. The Christian woman, who requested anonymity for security reasons, said Issavi’s wife, Medline Nazanin, visited the pastor at the unmarked facility. Nazanin said it was obvious Issavi had been tortured, the Christian told Compass.

Issavi’s confinement cells were so filthy he contracted a life-threatening infection, Nazanin told the Christian woman.

“They took him to the hospital and then returned him back to the prison,” the woman said.

Friends of Issavi added that he is still dealing with the lingering effects of the infection.

During Issavi’s imprisonment, authorities threatened to execute him, sources close to the case said. The joy of Issavi’s family at his release was tinged with fear as they waited in agony for the possibility of him being killed by Islamic extremists, as is common in Iran when Christians are detained for religious reasons and then released.

“Sometimes they release you just to kill you,” the Christian source said.

Issavi has not been informed of his trial date.

Issavi’s friend said that low-key ethnic Christians, such as the Assyrians, are largely unbothered for long periods of time. Active Christians are treated differently.

“When you start evangelizing, then you are in real trouble,” she said.

Iranian authorities have set up a video camera outside Issavi’s church to monitor anyone going in or out of the building, according to the pastor’s friend.

Issavi was one of a few Christians in leadership positions arrested in Isfahan in February during what some Middle Eastern experts described as a crackdown on area church leadership.

Isfahan, a city of more than 1.5 million people located 208 miles (335 kilometers) south of Tehran, has been the site of other anti-Christian persecution. In an incident in July 2008, two Christians died as a result of injuries received from police who were breaking up a house meeting.

On Feb. 28, Isfahan resident Hamid Shafiee and his wife Reyhaneh Aghajary, both converts from Islam and house church leaders, were arrested at their home.

Police handcuffed, beat and pepper-sprayed Aghajary and then took her to prison. Her husband Shafiee, who was away from the house when police arrived, was arrested an hour later when he returned to the house. Approximately 20 police officers raided the home, seizing Bibles, CDs, photographs, computers, telephones, personal items and other literature.

The couple is still being held. Other details about their detainment are unknown.

Three Christians Released

Elsewhere, three Christians arrested on Dec. 24, 2009 have been released, according to Farsi Christian News Network (FCNN).

Maryam Jalili, Mitra Zahmati, and Farzan Matin were initially arrested along with 12 other Christians at a home in Varamin. Eventually they were transferred to Tehran’s notorious Evin Prison, though the other 12 prisoners were conditionally released on Jan. 4. 

Jalili, Zahmati and Matin were freed on March 17, though terms of their release were unclear. Jalili is married and has two children.

Iran has a longstanding history of religious repression. Shia Islam is the official state religion and is ensconced as such in Iran’s constitution. Every year since 1999, the U.S. Secretary of State has designated Iran as a “Country of Particular Concern” for its persecution of Christians and other religious minorities.

According to the 2009 International Religious Freedom Report issued by the U.S. Department of State, persecution of Christians and other religious minorities in Iran continued to get significantly worse.

“Christians, particularly evangelicals, continued to be subject to harassment and close surveillance,” the report states. “The government vigilantly enforced its prohibition on proselytizing by closely monitoring the activities of evangelical Christians, discouraging Muslims from entering church premises, closing churches, and arresting Christian converts.”

Report from Compass Direct News 

New Dimension in India’s Anti-Christian Violence Feared

Concern grows that Hindu terrorists could become more apt to target Christians.

PUNE, India, November 5 (CDN) — After the recent arrests of numerous Hindu terrorists for exploding bombs, authorities increasingly view Hindu rightwing extremists as a threat not only to Muslim and Christian minorities but also to national security.

Historically Hindu terrorist groups have traded blows with India’s Muslim extremists, but because of a perceived threat from Christianity – as one Hindu extremist leader expressed to Compass – many analysts believe Hindu terrorists increasingly pose dangers to Christians as well.

Police in Goa state arrested two members of Hindu terrorist group Sanatan Sanstha (Eternal Organization) on Saturday (Oct. 31) for their alleged role in an explosion that took place near a church in Margao on Oct 16. Christians, which make up more than 25 percent of the 1.3 million people in Goa, were apparently not the target of the explosion, which occurred accidently when two members of the Sanatan Sanstha were trying to transport explosives to a nearby location on the eve of the Diwali Hindu festival, according to DNA newspaper.

Nevertheless, the incident served as a wake-up call to Christian leaders and others who fear Hindu terrorists could take greater aim at the Christian community. John Dayal, secretary general of the All India Christian Council (AICC), said that while terrorism was not new for rightwing groups, some of the extremist groups had “metamorphosed into fully fledged terrorism squads on classical lines – cells with local leaders, supply lines, bomb-making experts, and clear linkage with the intellectuals and motivators in the RSS [Hindu extremist Rashtriya Swayamsevak Sangh] hierarchy.”

Suresh Khairnar, a civil rights activist who has conducted nearly 100 fact-finding trips on communal incidents, told Compass that Muslims may be the main target of Hindu terrorist outfits, but “there is no doubt that they pose a threat to the Christians also.” He added that these Hindu groups also launch attacks on Hindus from time to time – masquerading as Islamist groups to create communal unrest, as well as to confuse investigating agencies.

Asghar Ali Engineer, chairman of the Centre for Study of Society and Secularism in Mumbai, concurred that Christians have increasingly become a secondary target for rightwing Hindu terrorists behind Muslims, who form 13.4 percent of the population.

“Christians, on the other hand, are only 2.3 percent,” said Engineer. “And because of their engagement with education, medicine and social work, it is difficult to promote anti-Christian sentiments.”

A former inspector general of police of Maharashtra, S.M. Mushrif, also said that while Muslims are the prime target of Hindu terrorists, attacking Christians also helps the Hindu assailants to portray themselves as “working for a Hindu cause.”

Members of suspected terror groups are known to have attacked Christians. On June 27, Shailendra Chauhan, alias Uday Singh – suspected to be a close aide of Sadhvi Pragya Singh Thakur, the prime suspect in a September 2008 blast in Malegaon, Maharashtra – was arrested for allegedly killing a Christian priest in Noida, a satellite town of Delhi. The 25-year-old Chauhan was also accused of vandalizing a church building in Sangam Vihar in Delhi in October 2008, according to The Times of India.

The AICC’s Dayal added that Islamic groups are the immediate target of Hindu terrorist groups, “but once the terror gangs of Hindutva [Hindu nationalist ideology] taste blood, it is easy to predict that they will swing into action against any perceived enemy target.”

How Alleged Terrorist Group Views Christians

The Anti-Terrorism Squad (ATS) of Mumbai is investigating powerful bomb blasts in Malegaon town, Maharashtra, allegedly carried out by members of the Hindu nationalist Abhinav Bharat (Pride of India) in September 2008. Compass spoke with the president of Abhinav Bharat about the alleged terrorist group’s attitude toward Christians.

The Malegaon blasts near a mosque killed six people and injured more than 100. The ATS arrested 11 people, including a serving officer of the Indian Army, from the Abhinav Bharat and other rightwing outfits.

The president of the Abhinav Bharat, Himani Savarkar, told Compass that members of her organization had been falsely accused, saying “The government is lying about their involvement. There is collusion between Muslims and the government.”

Asked if only Muslims were a threat to Hindus, she said, “There is danger from both Muslims and Christians, because of conversions and terrorism.”

Conversion represents a threat in that people converting to Islam change their loyalties from India to Mecca, while the loyalties of converts to Christianity shift from India to the Pope, Savarkar said. She also spoke of a more direct threat in Christianity – “Muslims want to kill the kafirs [unbelievers], and even Jesus asks in the Bible to kill all those who do not believe in Him” – and it is not known how many other Hindu extremists share this fallacy.

The number of Hindus, she added, “is slowly reducing, and one day we will become a minority in our own nation. We do not have any other nation.”

Savarkar, niece of Nathuram Godse, a Hindu nationalist who killed Indian independence leader Mahatma Gandhi in January 1948, said that in her view the main reasons people convert away from Hinduism are poverty and illiteracy.

“They do not know what they are doing,” she said. “We have to awaken Hindus. Hindus need to be made aware of the threats.”

Violent Despair

The use of bombs is a sign of frustration among extremists, said civil rights activist Khairnar, referring to the two successive defeats of the Bharatiya Janata Party (BJP), political wing of the Rashtriya Swayamsevak Sangh (RSS), India’s chief Hindu nationalist conglomerate. The BJP, which ruled the federal government from 1998 to 2004, has lost both the 2004 and 2009 general elections.

“They are now exploding bombs because they know they cannot succeed democratically,” he said, though he added that bomb-making per se was not a new development. “Even Nathuram Godse, the killer of Mahatma Gandhi, launched several bomb attacks before finally succeeding in assassinating him.”

In the case of the Malegaon blasts, Dayal said that the involvement of Hindu religious leaders and former army personnel indicated that terror attacks by rightwing Hindu groups were well planned. Security analysts warn that the extremist groups must be prevented from graduating to bigger terror groups.

On Oct. 21, the Mumbai Mirror daily quoted an ATS officer as saying Hindu extremist groups “are putting up a mild face as an organization while their members are detonating bombs. It’s only a matter of time before they begin to acquire better technology and more lethal bombs. Their influence is growing; there are several politicians and even ex-policemen who owe allegiance to them. They can be dangerous if not stopped now.”

O.P. Bali, former director general of police of Maharashtra, told Compass that until 2003, the year he retired, extreme Hindu nationalist groups like the Bajrang Dal mainly used weapons like sticks, tridents and knives.

“Bomb-making is a newer development, and they are still learning,” Bali said. “Considering the way some local Islamist groups have graduated from making and detonating of small bombs to bigger ones, the efforts of rightwing groups must be nipped in the bud.”

Hindu/Muslim violence has a long history. In 1947, when India became politically independent, British colonial India was divided into “Hindu-majority” India and “Muslim-majority” Pakistan. The partition resulted in the killing of around 1 million people – Hindu, Sikh and Muslim – in violent clashes mainly during the mass migration of around 14.5 million people from India to Pakistan and vice versa.

Engineer said the common notion that increasing modernization in India would put a halt to the growth of extremist groups was mistaken.

“Extremism is a reaction to modernization, and therefore such groups will grow even bigger in the future.”

Dayal seconded Engineer, saying the rightwing extremist groups were trying to keep pace with Islamist groups.

“Fortunately, in most areas, government vigilance, civil society and good relations between communities have kept these terror groups at the margins,” Dayal said. “But with the growth of parties that use identity-based divisive issues such as the Maharashtra Navnirman Sena party, with the apathy of government in BJP-ruled states, and with the middle-class support base for them, I fear such Hindutva terror groups may grow. That has been the historical experience in Western Europe and elsewhere.”

When suspects in the Malegaon blast were formally charged in January 2009, ATS officials told the court that the alleged terrorists’ goal was formation of a Hindu nation – and that the suspects planned to approach Israeli intelligence for help in combating Muslim extremists if the need arose, according to a Jan. 21 article in The Hindu.

Following numerous arrests, The Times of India daily on Oct. 21 quoted senior police officials as saying that Maharashtra was fast becoming a “hub of rightwing organizations’ terror activities.”

“The youth are being indoctrinated by fundamentalist organizations,” an officer told the daily. “The state should act quickly to control rightwing terror.”

Report from Compass Direct News 

Eritrea evangelical believers imprisoned with no sentence

For over seven years now, since May 2002, evangelical believers in Eritrea have been under persecution. Around 2800 sit in prison cells, military and labor camps, or metal shipping containers because prisons have run out of cells, reports MNN.

Aside from Orthodox, Catholic and Lutheran, any Christian gathering has been deemed “illegal” there because they have not been registered. However, Paul Estabrooks with Open Doors said that on numerous occasions they have tried to register, but they have hit roadblocks or the government has not allowed them.

Sadly, the situation has only grown worse. On September 6, the Eritrean government met together to discuss the growing numbers of arrests. The numbers concerned them because it indicated that people still continue to meet and worship. In response, the government met and “called on all the citizens of the country to inform the police of any illegal gatherings of Christians in their neighborhoods,” Estabrooks said.

Naturally, this has increased fear among Christians. However, as the government suspected, the church has been growing, albeit in a limited, covert way.

Estabrooks said believers expend a lot of energy keeping their worship secret while still maintaining their witness and sharing Christ with those around them. He said the church has remained strong, but believers are still under a significant amount of pressure. He also said Satan is using every tactic he can against them, especially intimidation.

In addition to the recent government crackdown, another believer died just recently while imprisoned. Because of horrible living conditions and lack of medical attention, Mesfin Gebrekristos died of meningitis. He left behind a wife and two children. Gebrekristos is the fourth believer to die this year and the tenth since the government started imprisoning Christians.

Estabrooks asked for people to pray diligently for the non-imprisoned believers in Eritrea. Pray for their continued strength and boldness.

“We’ve been asking for prayer for those in prison, for the family members of those in prison, and even for the government that God would miraculously somehow bring them to repentance,” Estabrooks said.

Report from the Christian Telegraph 

VIETNAM: POLICE ATTACK HOUSE CHURCH, JAIL LEADERS

Officers hit pastor, elder of house church; attempt to register denied on specious grounds.

HANOI, June 18 (Compass Direct News) – Police invaded the Sunday service of the Agape Baptist congregation in Vietnam’s Hung Yen Province on June 7 and beat worshippers, including women, and arrested a pastor and an elder.

Christian sources said police put the two church leaders into separate cells, and each man was beaten by a gang of five policemen. Pastor Duong Van Tuan of the house church in Hamlet 3, Ong Dinh Commune, Khoai Chau district said that officers beat them in a way that did not leave marks: hard blows to the stomach.

The beatings came in retaliation for Pastor Tuan refusing to leave the area as police had ordered, Christian sources said. He and the church elder were released later that evening.

The congregation in Hung Yen, a small but populous province that straddles the Red River 50 kilometers (31 miles) south of Hanoi, has endured harassment and attacks by police and other officials since April. Police officers disrupted worship services on April 19, bloodying Pastor Tuan’s mouth with punches, and also on May 24 and 31.

In the May 31 incident, he was attacked as he preached. The deputy commune police chief, identified only by his surname of Them, grabbed him by the neck while another officer tore the Bible from his hand, Christian sources said. His arms were twisted behind his back and “he was marched off like a criminal gang member,” one said.

Authorities took Pastor Tuan to the office of the commune people’s committee, clubbing him several times en route. Immediately after arriving at the office, police tried to force him to sign a document saying he had resisted their investigation, though he had yet to be questioned, and said that he was under administrative arrest. Christian sources said he was also ordered to sign a document accepting the seizure of his Bible, which they had taken from him two hours prior.

Officers ended by issuing him an order “to leave the commune immediately by the most direct route.”

A woman from his congregation who was unable to obtain cooperation from authorities at lower levels, Le thi Nhung, prepared and sent a detailed, three-page petition to local, provincial and national authorities on June 1, a week before officers last stormed their worship service.

In the petition, Nhung explained that one of the first things Pastor Tuan did on his arrival in March was to explain to church elders how to register their congregation’s activities according to the Prime Minister’s Special Directive on Protestantism of 2005. This directive permits and urges local authorities to register house churches to carry on religious activities. Pastor Tuan also went to the local Fatherland Front chair, a woman identified only as Hao, explained the church’s aspirations and asked her to help them meet requirements.

The church elders submitted an application to register locally, in accordance with the directive. Authorities, however, did not respond within the 30-day period prescribed by the directive. On the 31st day, they sent a document denying registration.

Bogus Denial

Officials gave two reasons for denying registration, Christian sources said: that the congregation needed permission from higher authorities, including the central Bureau of Religious Affairs; and that in any event the Prime Minister’s directive applied only to churches on mountains and not to churches on plains.

Both reasons, local Christians said, are contrary to the directive.

The church’s petition to the government clearly spelled out two articles of the constitution (71 and 73) and four articles of Vietnam’s criminal code (87, 124, 129 and 33) that police and local authorities violated in attacking their church and pastor.

The petition also reflects awareness of related international affairs. It says that on national news in Vietnam on May 27, church members heard the appeal of Ministry of Foreign Affairs officials to the U.S. Congress to vote down a recommendation by some U.S. officials to return Vietnam to the U.S. list of worst religious liberty offenders as a “Country of Particular Concern.”

“Think of how much hard work by the government, the Ministry of Public Security and the Ministry of Foreign Affairs, has just been thrown into the ocean by the officials of Ong Dinh Commune,” the petition states.

It concludes with a respectful request to all appropriate government authorities to investigate and “to help us law-abiding, tax-paying citizens of Khoai Chau District who practice pure and orthodox religion to peacefully practice our faith as a right protected by the State.”

In separate letters to supporting friends abroad, the leaders of the Agape Baptist House Church group, with 34 congregations throughout Vietnam, say that according to their long experience, “persecution is often a sign that the Lord is at work.” They add that they are not discouraged and see a growing maturity among Christians who suffer and overcome such gratuitous abuse. But they also say they feel much pain in seeing their Christian family disrespected, mistreated and abused.

The experience of this congregation is not uncommon, Christian sources said. Other unregistered house church groups report their requests for registering local congregations are being either ignored or denied.

Compass sources said they rarely see such abuse as well-documented as in this case. Said one advocate, “It would be very easy for authorities to follow this up and do the right thing, but few expect they will. It illustrates once more the famous Vietnamese maxim, ‘The law of the Emperor yields to the custom of the village.’”

Report from Compass Direct News

EGYPT: TWO COPTS WRONGLY DETAINED, TORTURED

Government uses brothers as scapegoat in murder; officials claim violence not sectarian.

ISTANBUL, December 1 (Compass Direct News) – Two Coptic Christians wrongfully arrested for killing a Muslim during the May 31 attack on Abu Fana monastery in Egypt have been tortured and sent to a detention camp so authorities could try to extract a false confession, their lawyer said.

Egyptian authorities sent brothers Refaat and Ibrahim Fawzy Abdo to El Wadi El Gadid Detention Camp near the Egypt-Sudan border on Nov. 22. A week earlier they were bailed out pending their court case – but never released – and held in a Mallawi police station until their transfer to the camp.

The brothers’ attorney, Zakary Kamal, said the timing of the murder at the monastery rules out any possibility of the two Copts having committed it.

Monks at Abu Fana say the Fawazy Abdo brothers were far from the monastery at the time of the May 31 attacks, which began at roughly 4 p.m. and continued until police arrived four hours later.

Security forces are detaining the brothers to blackmail the Coptic Church into testifying that the attack against Abu Fana monastery in Mallawi, Upper Egypt, was not religiously motivated, Kamal said.

“They want the whole issue to be seen by the public as if it were an exchange of gunfire and a criminal case that had nothing to do with persecution of Christians,” he told Compass.

At the beginning of Refaat and Ibrahim Fawzy Abdo’s captivity in June, police subjected the two men to electric shocks eight hours a day for three days to try to force them to testify that the Abu Fana monks were armed during the attack, sources said.

Kamal said those guilty in the attack knew the brothers were innocent but attempted to extort 5 million Egyptian pounds (US$920,000) from the Coptic church in exchange for testimony in support of the brothers during informal “reconciliation meetings.”

Such meetings are somewhat customary in Egypt, in which different parties come together to settle legal matters out of court. Egyptian parliamentarians attended the first meetings, but the parties did not reach a settlement.

Kamal said he worries that police and parliamentarians are using the meetings to pressure the Coptic Church to agree to their terms and take the focus of the case off of rising sectarian violence within Egypt.

Reconciliation meetings are part of a larger trend in Egypt of the government framing such clashes as cases of simple land disputes with no sectarian overtimes, the attorney claimed, and so far he has refused to pay money in exchange for a testimony.

“I completely refused any agreements of reconciliation, because if we accept those terms, that means we admitted [the brothers] killed someone,” he said.

The two men worked as building contractors on the walls of Abu Fana monastery when nearly 60 armed Muslim residents attacked it on May 31. The attack left one Muslim dead, four Christians injured, and three monks briefly kidnapped.

Ibrahim Tiqi Riad, the brother of resident monk Father Mina, was also kidnapped and remains missing. A Coptic priest who preferred to remain anonymous told Compass that they believe he may have been forcibly converted to Islam.

In the course of the violence, attackers tied two of the kidnapped monks to a palm tree, whipped and beat them, and forced them to spit on a cross and give the confession of Islam, according to a report by the Coptic Assembly of America.

Five days after the attacks, security forces arrested the Fawazy Abdo brothers, charging them with murder. Their case is pending.

The families of the two men are suffering in their absence as they were the sole breadwinners. The electricity in their families’ houses has been shut off since they can’t pay their bills, Kamal said.

The reasons behind the death of the Muslim at Abu Fana monastery remains a mystery. Police did not record the details of the killing in the investigation report of the monastery attack.

Bishop Demetrios Avanmina, head of the Mallawi diocese and abbot of Abu Fana monastery, is working to resolve the matter with local politicians and security forces.

Avanmina declined to comment to Compass on the brothers’ captivity, saying only that he and others were working with the police and the state to resolve the matter.

 

Government Spin

The nature of the May attacks against the monastery, located 200 kilometers (124 miles) south of Cairo, is in dispute. Coptic advocacy groups claim the attacks were motivated by growing hostility against Egypt’s Christian community.

But local Muslims say monastery leaders were illegally taking possession of land and attempting to frame the attacks in the form of religious persecution in order to gain sympathy for their cause.

Gov. Ahmed Dia el-Din said police reports have documented disputes over the land going back several years, and that Abu Fana obtained portions of its land from informal contracts, resulting in the governor’s rejection of the monastery’s claim of possessing valid land titles, according to Egyptian weekly Al-Maydan.

Following the attacks, hundreds of Coptic Christians took to the streets of Mallawi to demonstrate against the violence. They chanted, “With our blood and soul, we will defend the cross.”

The monastery has seen violent episodes in the past with its neighbors, typically over issues relating to land.

In January another group of a dozen men armed with automatic weapons burned the monastery’s library and destroyed many monastic cells, according to the Coptic Assembly advocacy group.

The Coptic Church makes up at least 10 percent of the Muslim-majority country’s population of 80 million. Its church dates back to the early centuries of Christianity.  

Report from Compass Direct News

ERITREA: CHRISTIANS LANGUISH IN ERITREAN PRISONS

Evangelist fears he will die in confinement.

LOS ANGELES, September 24 (Compass Direct News) – An evangelist imprisoned since 2006 for his Christian activities is receiving especially harsh treatment because of his ministry to inmates.

Sources said Teame Weldegebriel is on the brink of despair as he languishes at the Mai Sirwa Maximum Security Confinement prison.

“It seems that hell has broken loose on me,” Weldegebriel told Compass sources. “Please tell the brethren to continue praying for me. I am not sure I will see them again.”

Prison authorities consider Weldegebriel dangerous because of his boldness in sharing his faith. The Rhema Church evangelist has been proclaiming Christ to other prisoners, and many have converted to Christianity.

“This has made him to be in bad books with the prison wardens,” one source said.

Weldegebriel’s family is worried about his health after trying repeatedly, without success, to get permission to visit him.

Inmates at the prison often go hungry and are said to be feeding on leaves.

In Eritrea, a nation with a government of Marxist roots where about half of the people are Muslim, two or more people gathered in Jesus’ name can be imprisoned for not practicing their faith in one of the government-sanctioned Orthodox, Catholic, Lutheran or Muslim bodies.

More than 2,000 Christians in Eritrea are imprisoned for their faith, including a Christian from a Full Gospel Church who was arrested in 2001. His wife last saw him in June 2007. She and her two minor children were rounded up from a prayer meeting in mid-July and placed in a metal shipping container until their release last month, she said.

“I was arrested with my children while having a prayer meeting with 20 other Christians,” said the woman, who requested anonymity for security reasons. “They locked us up at a military concentration camp, inside metal ship containers. I remember the horrible ordeal I went through with the children. After three weeks I was released with my two children, while the other Christian soldiers remained locked in the prison cells.”

The government views leaders of large unregistered bodies like the Full Gospel Church and Rhema Church as threats, according to Christian sources in the country. Eritrean officials fear the church leaders will expose the abuses and conditions in the prisons. Hence it is extremely difficult for relatives to see those in prison, and inmates are not allowed to send or receive letters.

“The government has been transferring them from one prison cell after another,” said one Christian source in Asmara.

In May 2002 the government criminalized all independent churches not operating under the umbrella of the Orthodox, Lutheran, Catholic, and Muslim religious structures.

 

Arrested for Talking

In the seaport city of Massawa, police in June arrested a man and a woman, both Christians, who were talking to Muslims about Christ. Members of Kale Hiwot Church, the two were discussing their Christian faith when four plainclothes policemen arrested them.

“It took about 30 minutes talking about Jesus before they were both arrested by the police – they had witnessed about Jesus and the faith for a long time to some Muslims,” another source told Compass. “I watched the two Christians whisked away by the police. They were taken to join more than 100 Christians imprisoned in Waire prison about 25 kilometers [16 miles] from Massawa.”

A previously imprisoned evangelist with the Full Gospel Church in Asmara who requested anonymity told Compass that God is at work in Eritrea, with many people converting to Christ and receiving divine healing.

“For sure Christians are getting imprisoned, but God’s word cannot be imprisoned,” he said. “I am ready for any eventuality, including being imprisoned again. On several occasions, prison wardens warned me to stop preaching, though they still loved me. Indeed Jesus loved me. They saw God in me.”

The U.S. Department of State notes in its 2008 International Religious Freedom Report that Eritrea has not implemented its 1997 constitution, which provides for religious freedom. The state department has designated Eritrea as a Country of Particular Concern, a list of the worst violators of religious freedom, since 2004.

Many of the more than 2,000 Christians under arrest in police stations, military camps and jails across Eritrea because of their religious beliefs have been incarcerated for years. No one has been charged officially or given access to judicial processes.

Reliable statistics are not available, but the state department estimates that 50 percent of the population is Sunni Muslim, 30 percent is Orthodox Christian, and 13 percent is Roman Catholic. Protestants and Seventh-day Adventists along with Jehovah’s Witnesses, Buddhists, Hindus, and Baha’is make up less than 5 percent of the population.

Report from Compass Direct News